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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Abdominal proctocolectomy & Ulcerative colitis (UC)

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The standard treatment for refractory ulcerative colitis (UC) or UC with colonic dysplasia is a total Abdominal Proctocolectomy & Preclinical/Clinical Data & Monotherapy with ileal pouch-anal anastomosis (IPAA).
Santiago et al. 2024 Inflammatory Bowel Diseases 30(7): 1062-1070

Approximately half of the patients with Ulcerative colitis (UC) who undergo IPAA develop pouchitis, while chronic pouchitis (CP) occurs in 5% to 10% of these patients.
Quinn et al. 2019 Inflamm Bowel Dis 25(3): 460-471

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A comprehensive approach to pouch disorders
Quinn et al. 2019 Inflamm Bowel Dis 25(3): 460-471
Altered Bile Acid and Pouch Microbiota Composition in Patients With Chronic Pouchitis
Santiago et al. 2024 Inflammatory Bowel Diseases 30(7): 1062-1070
Ileal pouch-anal anastomosis and pouchitis: the role of the microbiota in the pathogenesis and therapy
Gabbiadini et al. 2022 Nutrients 14(13): 2610
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Abdominal proctocolectomy & Ulcerative colitis (UC)

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