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Generally, cellular stresses and inflammatory cytokines activate JNK (c-Jun N-terminal kinase)
Stress-Activated Protein Kinase / Jun N-terminal Kinase (SAPK / JNK), a member of the Mitogen-activated protein kinases (MAPKs or MAP kinases), was originally identified as a stress-activated kinase linked to the death response. More recently, it has been shown to have additional cellular functions, playing a key role in cell growth, differentiation, and survival.
Stress-Activated Protein Kinase / Jun N-terminal Kinase (SAPK / JNK) is a central component in the [Stress-Activated Protein …