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Shown is the Choline degradation pathway
The generation of Trimethylamine-N-Oxide (TMAO) begins with the gut microbiota converting dietary compounds (here: phosphatidylcholine) into trimethylamine (TMA) due to Choline TMA Lyase activity.
Specific bacterial genes, such as the cutC gene encoding [choline TMA-lyase](brain://Xso8kBoYkEyWpoV7IYiBfg/CholineTmaLy…