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Metoclopramide may have several adverse effects on the cardiovascular and nervous systems, which might be resolved with a new intranasal preparation
Somnolence = drowsiness with abnormal sleepiness
Extrapyramidal Effects Which Include Dyskinesia, Dystonia, Convulsions, Hypertonia, Tremors, and Tardive Dyskinesia
The risk of tardive dyskinesia development was found to be greater in patients who took it for > 3 months
Due to the blood-brain barrier crossing, the use of metoclopramide is often limited by undesired side effects. These range from mild sedation and agitatio…