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Urolithin A, a metabolite of ellagic acid generated by gut microbes, could increase the sensitivity of colorectal cancer (CRC) cells to Fluorouracil (5-FU)
This finding suggests that a combination of Fluorouracil (5-FU) and ellagic acid may lead to 5-FU dose reduction and decreased toxicity and, most importantly, increased benefit from the reduced dose
Gut microbes inc…