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In the context of Immune Checkpoint Inhibitors (ICI) & Endometrial Cancer (EC), recent trials with immune checkpoint inhibitors used alone or in combination with other agents have demonstrated remarkable efficacy in treating the all-comers Endometrial Cancer (EC) patient population.
Immune checkpoint inhibitors have significantly changed our approach to the treatment of advanced/recurrent Endometrial Cancer (EC). Single agent anti-PD-1 regimens are highly effective in MMRd/MSI-H patients, but their clinical efficacy remains modest in MMR proficient/TMB low EC patients. Combination regimens that can decrease the tumor microe…