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Cyclin-dependent kinase 1 (CDK1) inhibitors have a potential as effective chemotherapeutic agents.
A series of Ruthenium-Arene-β-Carboline Complexes has been reported as potent Cyclin-dependent kinase 1 inhibitors, showing high anticancer activity and the ability to overcome cross-resistance to cisplatin
Additionally, Thioflavopiridols and oxoflavopiridols have been identified as selective Cyclin-dependent kinase 1 inhibitors with significant antipro…