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Primary Purpose : Treatment
Allocation : N/A
Interventional Model : Single Group Assignment
Masking : None (Open Label)
Primary outcome measures:
Intracranial progress free survival rate
The authors concluded that treatment using hypofractionated stereotactic radiotherapy (HFSRT) concurrent with temozolomide (TMZ) was well tolerated and could significantly extend OS compared with historical controls in complex brain metastases. Large randomized clinical trials are warranted.
Bi et al. 2019
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