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Ceramide acts as an intracellular signaling molecule that can induce apoptosis in different cell types. It is implicated in the signal transduction of catabolic cytokines such as tumor necrosis factor (TNF) and interleukin-1 (IL-1), which are known to promote cell death
Ceramide increases the expression of matrix metalloproteinases (MMPs), including Matrix metalloproteinase (MMP)-1, [Matrix metalloproteinase (MMP)-3 (…