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While epithelial hypoxia and dysbiosis are distinct conditions, they can intersect in their impact on health. For instance, hypoxia in the gut or respiratory tract could potentially alter the local microbiota, contributing to dysbiosis. Conversely, dysbiosis might exacerbate inflammation and tissue damage, potentially worsening hypoxia in affected tissues.
Hypoxia can disrupt the integrity of epithelial barriers by reducing the expression of [tight junction proteins](brain://j-Dx9z5QZEq_OuxncREgjw/TightJunctionMoleculesTightJunctionProteins…