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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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CD276 (B7 homolog 3 protein (B7-H3)) & Cancer / Tumors

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Cancer-aberrant expression of B7-H3 in various human malignancies including melanoma, glioma, leukemia, lung, pancreatic, renal, colorectal, ovarian, breast, gastric and endometrial cancers was detected in 60–93% of the tumor tissue, while limited expression is seen on normal healthy tissues
Picarda et al. 2016 Clin Cancer Res. 22(14): 3425–3431

CD276 (B7 homolog 3 protein (B7-H3)) expression in hepatocellular carcinoma (Sun et al. 2012 Cancer Immunol Immunother. 61(11): 2171–2182), endometrial carcinoma (Brunner et al. 2012 Gynecol Oncol. 124(1): 105–111), [osteosarcoma](brain://vfv-jIbit0u20UelfxbOvA/BoneCancerOsteosarcomaOsOsteogen…

References (Sources)

B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer
Ingebrigtsen et al. 2012 Int J Cancer 131(11): 2528–2536
B7-H3 is expressed in human hepatocellular carcinoma and is associated with tumor aggressiveness and postoperative recurrence
Sun et al. 2012 Cancer Immunol Immunother. 61(11): 2171–2182
B7-H3 is overexpressed in patients suffering osteosarcoma and associated with tumor aggressiveness and metastasis
Wang et al. 2013 PLoS One. 8(8): e70689
Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response
Chen et al. 2015a Proc Natl Acad Sci USA 112(42): 13057–13062
Immunoexpression of B7-H3 in endometrial cancer: relation to tumor T-cell infiltration and prognosis
Brunner et al. 2012 Gynecol Oncol. 124(1): 105–111
Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy
Picarda et al. 2016 Clin Cancer Res. 22(14): 3425–3431
Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas
Zang et al. 2010 Mod Pathol. 23(8): 1104–1112

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7/1/2026

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