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Dong et al. 2013 Eur J Nutr 52: 1853–1863 published the results of a probiotic drink containing 1.3 × 1010 CFU Lactobacillus casei Shirota or skimmed milk per day for 4 weeks to healthy old volunteers from a randomized placebo-controlled, single-blind crossover study with 30 subjects.
The authors' conclusion was: Consumption of a probiotic drink containing Lactobacillus casei Shirota improved NK cell activity and tended to produce a more anti-inflammatory cytokine profile in an older population.
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