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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Cancer / Tumors & Signal transducer and activator of transcription 3 (STAT3)

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Signal transducer and activator of transcription 3 (STAT3) is involved in cancer initiation and resistance to chemo-radiation therapies and targeted agents.
Santoni et al. 2021 Expert Opin. Investig. Drugs 30: 245-251

Rhus coriaria suppresses angiogenesis, metastasis and Tumor growth of breast cancer through inhibition of Signal transducer and activator of transcription 3 (STAT3), NFKB and nitric oxide pathways
El Hasasna et al. 2016

References (Sources)

An update on investigational therapies that target STAT3 for the treatment of cancer
Santoni et al. 2021 Expert Opin. Investig. Drugs 30: 245-251
Review
Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways
El Hasasna et al. 2016
STATs in cancer inflammation and immunity: a leading role for STAT3
Yu et al., 2009
Review
Targeting STAT3 with silibinin to improve cancer therapeutics
Bosch-Barrera et al. 2017 Cancer Treatment Reviews 58: 61-69

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7/1/2026

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Cancer / Tumors & Signal transducer and activator of transcription 3 (STAT3)

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