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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Adenosine & Immune Responses

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Adenosine mediates immunosuppression
Augustin et al. 2022 Journal for ImmunoTherapy of Cancer 10: e004089

A2aR signaling on antitumor T cells inhibits effector responses and protects tumor development
Ohta et al. 2006 Proc Natl Acad Sci USA 103:13132–13137

A2A adenosine receptor protects tumors from antitumor T cells
Ohta et al. 2006 Proc Natl Acad Sci USA 103: 13132-13137
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
Zarek et al. 2008 Blood 111:251–259
Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy
Augustin et al. 2022 Journal for ImmunoTherapy of Cancer 10: e004089
Review
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
Ohta & Sitkovsky 2001 Nature 414:916–920

7/1/2026