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Intestinal bifidobacteria could promote the maturation of dendritic cells and its expression of IL-12 locally in the gut, influence the development of T cells in the thymus, favor the development of T-helper cell type 1 response by increasing the local and systemic expression of interferon-gamma and ensure the intestinal regulatory T cell response by promoting the local expression of IL-10. In addition, they enhance antibody synthesis by PBMCs, …