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Immune checkpoint inhibitors (ICIs) have shown significant therapeutic effects in the treatment of small-cell-lung cancer (SCLC).
Clinical trials have evaluated the efficacy of ICIs, such as PD-1 inhibitors (e.g., pembrolizumab and nivolumab), as first-line therapy for Small-Cell-Lung-Cancer (SCLC).
A systematic review and meta-analysis of 16 relevant clinical trials comprising 4,476 patients found that ICIs as first-line therapy conferred a statistically significant benefit in overall survival.
He & Hu 2023 Front Immunol.14: 112…