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Treatment ranges from observation to allogeneic hematopoietic stem cell transplantation. Therapies include hydroxyurea for cytoreduction, hypomethylating agents, and the JAK1/2 inhibitor ruxolitinib to address splenomegaly and constitutional symptoms.
Chronic myelomonocytic leukemia (CMML) is a hematologic disorder with no curative therapies with exception of allogeneic transplant. Therapeutic options for patients with [Chronic Myelomonocytic Leukemia](brain://FMhb7rgPLE-TOcQ5JojIrw/ChronicMyelomonocyticLeuk…