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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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CD134 / OX40 receptor antibodies

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CD134 / OX40 receptor antibodies are designed to target the CD134 / OX40 receptor antigen, a 50 kDa type I transmembrane glycoprotein belonging to the tumor necrosis factor receptor (TNFR) superfamily.

Some CD134 / OX40 receptor antibodies, particularly those with mIgG1 isotypes, directly stimulate T-cells by acting as agonists to the CD134 / OX40 receptor
Willoughby et al. 2024 J Immunother Cancer 12(7): e008677

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Impact of isotype on the mechanism of action of agonist anti-OX40 antibodies in cancer: implications for therapeutic combinations
Willoughby et al. 2024 J Immunother Cancer 12(7): e008677

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7/1/2026

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CD134 / OX40 receptor antibodies

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