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In the context of Axitinib + Pembrolizumab & Clear Cell Renal Cell Carcinoma (ccRCC), Axitinib + pembrolizumab is approved by both the FDA and EMA as a first-line treatment for advanced or metastatic clear cell renal cell carcinoma (ccRCC). This combination became a standard frontline therapy following the KEYNOTE-426 phase III trial, which demonstrated superior overall survival and progression-free survival compared to sunitinib monotherapy in patients with advanced ccRCC (1, 2, 3…