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Advances in immune checkpoint inhibitors have positive implications for the radiotherapy abscopal response
Tubin et al. 2020 Future Oncology 16: 1137-1151
Regression of distant, non-irradiated tumor sites after radiation therapy alone may occur more frequently in combination cancer immunotherapy
Tubin et al. 2020 Future Oncology 16: 1137-1151
Recently, clinical trials have focused on combinations of ICB with radiation therapy. Although two recent Phase III randomized trials demonstrated improved survival with adjuvant ICB following chemoradiotherapy, other Phase I/II/III trials are either negative or inconclusive, but do yield suggestive results and promising insights into future therapeutic strategies.
Pointer et al. 2022 Trends in …