ChiCTR2300074826 - Bifidobacterium breve BB-05 & Psychosomatic diarrhea

Study overview

It is a randomized, double-blind, placebo-controlled trial studying 1 × 10^10 CFU per packet of live Bifidobacterium breve BB-05 or placebo in 100 recruited students experiencing gastrointestinal symptoms, specifically diarrhea (BSS diarrhea scores of 5-7) twice daily for 2 consecutive weeks (1)

Outcome measures

• Bristol Stool Scale (BSS): Used to assess stool formality following episodes of diarrhea


• 14-item Hamilton Anxiety Scale (HAMA-14): Evaluates anxiety levels.


• 17-item Hamilton Depression Rating Scale (HDRS-17): Measures depression severity (1)

Results

Bifidobacterium breve BB-05 supplementation has been shown to significantly enrich the [reduced gut microbial diversity](brain://8nIPcskIKk2mxtbgCVZMHw/Redu…