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Bacteroides cellulosilyticus LYH2 shows a wide range of antimicrobial effects and can suppress macrophage infections while reducing pro-inflammatory gene expression in laboratory settings. Long-term oral use in mice is safe and leads to better metabolic health. In a model of DSS-induced colitis, B. cellulosilyticus LYH2 is more effective than a reference Bacteroides strain, mesalamine, and Lactobacillus reuteri in reducing inflammation and restoring [goblet cell](brain://6apOJNLb2k2tt5d7sPX69Q/Goble…