Classic ketogenic diet (4:1) / Standard ketogenic diet (SKD) & Cancer / Tumors

Lipids present in ketogenic diet could compensate for reduced lipid synthesis in tumor cells to enable survival under glucose-restricted conditions. Interestingly, when the ketogenic diet was made from palm oil instead of lard tumor, growth was inhibited, due to excess levels of saturated fatty acids, which were toxic to tumor cells
McIntyre et al. 2023 Trends in Cancer 9: 752

There is evidence of ketogenic diet promoting CD8 T cell cytotoxicity to reduce tumor growth
Lussier et al. 2016 BMC Cancer 16: 310
Sun et al. 2022 J. Funct. Foods 92: 105067

Ketogenic diet treatment can enhance the anti-tumor immunity and mitigate the tumor immunosuppression in the tumor microenvironment, as well as decrease the tumor vascularization in a CT26 model
Sun et al. …