TFPI is highly expressed in the intestinal glands, and recombinant TFPI protects the colonic epithelium from TcdB2/TcdB4. Luo et al. 2022 Cell 185: 980-994
TFPI as a colonic crypt receptor for TcdB from clade 2 C. difficile and reveal new mechanisms for CDI pathogenesis. Luo et al. 2022 Cell 185: 980-994
