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Opisthorchis viverrini, a liver fluke endemic to Southeast Asia, is directly associated with the development of cholangiocarcinoma (CCA), a type of bile duct cancer.
This association is recognized due to the multifaceted mechanisms through which the parasite induces carcinogenesis.
The infection is primarily contracted through the consumption of raw or undercooked fish, a common dietary practice in regions where Opisthorchis viverrini is prevalent, such as Thailand, Laos, Vietnam, and Cambodia
Kaewpitoon et al. 2008 …