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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Group 1 ILCs (ILC1) & Inflammation / Inflammatory Diseases

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Crohn's disease (CD) and severe Chronic obstructive pulmonary disease (COPD) / Emphysema, for instance, are characterized by an ILC1-dominated immune response.
Schulz-Kuhnt et al. 2020

Under inflamed conditions, several human Group 1 ILCs (ILC1) subsets have been found to expand and produce excessive cytokines
Li & Glover 2018 Archivum Immunologiae et Therapiae Experimentalis 66: 415-421

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References (Sources)

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
Bernink et al. 2013 Nat Immunol 14: 221-229
Innate Lymphoid Cells in Inflammatory Bowel Disease
Li & Glover 2018 Archivum Immunologiae et Therapiae Experimentalis 66: 415-421
Review
Regulation of Human Innate Lymphoid Cells in the Context of Mucosal Inflammation
Schulz-Kuhnt et al. 2020
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Group 1 ILCs (ILC1) & Inflammation / Inflammatory Diseases

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