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Bacteroides fragilis NCTC 9343 induces a marked expansion of Tregs in the intestinal mucosa via Toll-like receptor 1 (TLR-1) / Toll-like receptor 2 (TLR-2) heterodimer (TLR-1/TLR-2) / MYD88 / NFKB signaling pathway—a response dependent on the presence of polysaccharide-A (PSA), a zwitterionic capsular polysaccharide
Bacteroides fragilis NCTC 9343 can also mediate protection against oxazolone-induced colitis in a PSA-independent …