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In addition to their predictive value, recent studies in patients with non-small cell lung cancer (NSCLC) have shown that CTCs can serve as predictive biomarkers for targeted therapies and immunotherapies, which may help determine their therapeutic responses.
Detection method under evaluation are: EpCAM-based immunomagnetic assay (most midely used), CD45-based immunomagnetic assay, Ligand-targeted PCR-based assay, Telomerase-based assay, Size-based assays.
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