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There are two types of suppressive mechanisms: Contact-dependent suppression and Cytokine-dependent suppression
| Key Molecule(s) | Function | Ref. |
|---|---|---|
| CTLA-4 | Downregulation of APC co-stimulatory function (mouse) Interaction with CD80 and CD86 on conventional T cells (mouse) | (1) (2) |
| CD73–CD39 | Hydrolysis of inflammatory extracellula… |