Cathepsin K inhibitors

Introduction

Cathepsin K inhibitors are a class of therapeutic agents that target cathepsin K, a cysteine protease predominantly expressed in osteoclasts, which plays a crucial role in the degradation of bone matrix, mainly Type I collagen.

Cathepsin K inhibitors specifically target bone matrix degradation without affecting osteoclasts' viability. This selective inhibition is considered advantageous because it potentially allows for the preservation of bone turnover processes necessary for maintaining bone health

see also:
Cathepsin K (Cat K) Inhibitors & Osteoarthritis / Arthrosis
[Cathep…