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The Notch gene is part of the transmembrane receptor family and plays a role in one of the most conserved signaling pathways known as the Notch signaling pathway. This pathway is crucial for intercellular communication and the regulation of cell fate. It oversees numerous vital biological processes, such as cell growth and the differentiation and maintenance of stem cells during both embryonic and adult development.
Notch signaling issues link to many human diseases. These include developmental problems and adult cancers. Recent studies show Notch affects both innate and adaptive immunity. This insight supports Notch-focused treatments for immune disorders.
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