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In the inflamed intestine of patients with Crohn’s disease (CD), Group 2 ILCs (ILC2) and ILC3s transdifferentiate into Group 1 ILCs (ILC1).
Numerous studies have found that Innate Lymphoid Cells (ILCs) also undergo a series of alternations during the development of Crohn’s Disease (CD) and contribute to this disease.
The incidence of type 1 ILCs and type 3 ILCs in the intestinal tract is higher in patients with Crohn’s Disease (CD) than in nor…