Omeprazole & Gastroesophageal reflux disease (GERD)

Omeprazole is an effective treatment for reflux esophagitis. Research has shown that omeprazole is superior to ranitidine in the short-term treatment of ulcerative reflux esophagitis, with complete healing observed in 50% of patients on omeprazole 20 mg daily compared to 20.7% on ranitidine 150 mg twice per day
Bianchi Porro et al. 1992 J Clin Gastroenterol. 15(3): 192-8

Additionally, omeprazole has been found to virtually eliminate esophageal exposure to a pH of less than 4 in patients with reflux disease
Dent et al. 1989 Scand J Gastroenterol Suppl. 166: 76-82

A long-term maintenance study also demonstrated that omeprazole is effective and safe in preventing relapses of severe reflux esophagitis
Koop & Arnold 1991 Digest Dis Sci 36: 552-557

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