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Progesterone promotes the development of human CD4+ Th2 cells and so antagonizes the emergence of the CD4+ Th1 Cells response. Similarly, testosterone has anti-inflammatory properties and exerts immunosuppressive effects in several animal models of autoimmunity
Sex hormones (such as progesterone) that promote the development of a TH2 response antagonize the emergence of CD4+ Th1 Cells
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