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For Alzheimer's disease (AD) treatment, US FDA granted accelerated approval for aducanumab due to its amyloid-beta (Aβ)-lowering effects, notwithstanding the reported poor correlation between amyloid plaque reduction and clinical change for this drug.
Aducanumab, a recently FDA-approved anti-Aβ monoclonal antibody has been greeted with distrust by most experts, hospitals and insurance companies for its level of efficacy and poor tolerability.
see also:
Immunotherapy & Alzheimer's Disease (AD)
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