Cardiovascular diseases (CVD) & Gut microbiota

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Gut microbiota affects cardiovascular health through intestinal inflammation.
Zhao et al. 2026 Front Microbiol 17: 1783688

Key pathways include Trimethylamine-N-Oxide (TMAO), Short-chain fatty acids (SCFAs), and bile acid metabolism affecting blood pressure, artery health, and heart failure.
Zhang et al. 2025b Front Microbiol 16: 1690411

The gut microbiota has been linked to cardiovascular diseases (CVD) such as [heart failure](brain://xGn8V9eGUE2EjJpvEy7jZQ/HeartFailu…

A cardiovascular disease-linked gut microbial metabolite acts via adrenergic receptors
Nemet et al. 2020 Cell 180: 862-877
A critical review on diet-induced microbiota changes and cardiovascular diseases
Jayachandran et al. 2020 Critical Reviews in Food Science and Nutrition 60(17): 2914-2925
Review
Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation
Chen et al. 2008 J. Immunol. 181: 7186-7193
Gut microbiome and cardiovascular disease
Zhao & Wang 2020a Curr. Opin. Cardiol. 35: 207-218
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
Tang et al. 2013 N Engl J Med 368: 1575-84
Pathogenic gut ﬂora in patients with chronic heart failure
Pasini et al. 2016 JACC Heart Fail 4: 220-227
Role of gut microbiota in cardiovascular diseases
Novakovic et al. 2020 World J Cardiol 12(4): 110-122
Review

8/24/2026