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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Interleukin-1 (IL-1) & NFKB Activation

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Contents

IL-1 induces translocation of NFKB into the nucleus, resulting in activation and transcription of inflammatory genes
O’Neill 2002 Curr Top Microbiol Immunol 270: 47-61
Delhalle et al. 2004 Ann N Y Acad Sci 1030: 1-13

It is unclear whether this effect is a specific IL-1 beta effect
Al-Sadi & Ma 2007 J Immunol 178(7): 4641-9
Al-Sadi et al. 2008 J Immunol 180(8): 5653-61
Gentile et al. 2015 Eur J Nutr 54(5): 811-21
Guo et al. 2017a J Pediatr Gastroenterol Nutr 64(3): 404-12

Although both the canonical (classical) and non-canonical (non-classical) [NFKB pathways](brain://mB1u-7g6F0WjLigZU5dcEg/NfkbSignalingNf…

References (Sources)

Beginner’s Guide to NF-Kappab Signaling Pathways
Delhalle et al. 2004 Ann N Y Acad Sci 1030: 1-13
IL-1beta Causes an Increase in Intestinal Epithelial Tight Junction Permeability
Al-Sadi & Ma 2007 J Immunol 178(7): 4641-9
IL-1beta-Induced Increase in Intestinal Epithelial Tight Junction Permeability is Mediated by MEKK-1 Activation of Canonical NF-Kappab Pathway
Al-Sadi et al. 2010 Am J Pathol 177(5): 2310-22
Involvement of Intracellular Signaling in the IL-1beta Inhibitory Effect on Fructose Intestinal Absorption
Rodriguez-Yoldi et al. 2015 J Cell Physiol 230(4): 896-902
Mechanism of IL-1beta-Induced Increase in Intestinal Epithelial Tight Junction Permeability
Al-Sadi et al. 2008 J Immunol 180(8): 5653-61
Sicilian Pistachio (Pistacia Vera L.) Nut Inhibits Expression and Release of Inﬂammatory Mediators and Reverts the Increase of Paracellular Permeability in IL-1bExposed Human Intestinal Epithelial Cells
Gentile et al. 2015 Eur J Nutr 54(5): 811-21
Signal Transduction Pathways Activated by the IL-1 Receptor/ Toll-Like Receptor Superfamily
O’Neill 2002 Curr Top Microbiol Immunol 270: 47-61

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