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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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RAR-related Orphan Receptor Gamma/T (ROR-gamma/t) Isoform 2 (NR1F3)t + Foxp3 + Colonic Treg cells & Muscle injury

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Colonic RORg +Treg cells that accumulate in skeletal muscle at early times after acute [injury]. Muscle ROR gamma + Treg cells have a colonic provenance.
(?id=73312c56-914c-5c70-a88f-2ec20e1aeba7&linkText=injury)Hanna et al. 2023 Immunity 56(4): 829-846

Muscle ROR gamma + Treg cells are microbiota dependent
Hanna et al. 2023 Immunity 56(4): 829-846

Colonic RORg + Treg cell accumulation in regenerating muscle depends on induction of soluble factors and TCR:MHC-II interactions
Hanna et al. 2023 Immunity 56(4): 829-846

Loss of muscle ROR gamma + Treg cells induces more local IL17A-producing cells and impairs muscle regeneration
Hanna et al. 2023 Immunity 56(4): 829-846

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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
Hanna et al. 2023 Immunity 56(4): 829-846

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RAR-related Orphan Receptor Gamma/T (ROR-gamma/t) Isoform 2 (NR1F3)t + Foxp3 + Colonic Treg cells & Muscle injury

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