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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Epithelial Barrier Integrity / Mucosal Barrier Integrity & Interleukin-18 (IL-18)

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Deletion of Interleukin-18 (IL-18) or its receptor IL-18R1 in intestinal epithelial cells conferred protection from colitis in mice
Nowarski et al. 2015 Cell 163: 1444–1456

Interleukin-18 (IL-18) maturation by the Nlrp3 inflammasome confers protection against DSS-induced colitis. Interleukin-18 (IL-18)(brain://uI3u9U6OC0eElPSNqZKTsQ/Interleukin18Il18) i…

Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity
Jarret et al. 2020 Cell 180: 50-63 e12
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Nowarski et al. 2015 Cell 163: 1444–1456
The NLRP3 inﬂammasome protects against loss of epithelial integrity and mortality during experimental colitis
Zaki et al. 2020 Immunity 32: 379-391

7/1/2026