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Human epidermal growth factor receptor 2 (HER-2) is an oncogenic driver and target in gastroesophageal and breast cancer; there is also evidence for a role in non-small cell lung cancer (NSCLC).
Ahn et al. 2022 Expert Opinion on Investigational Drugs 31(5): 437-441
The overexpression and/or amplification of human epidermal growth factor receptor 2 (HER2) occurs in approximately 20% of breast cancers (BC) and is a major driver of tumor development and progression.
Lu 2022 J Clin Oncol 40: suppl 16; abstr TPS1112
The HER…