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VSL#3 TM has been investigated as a therapeutic option for Diarrhea-predominant IBS (IBS-D), with several studies suggesting that it may improve overall IBS symptoms, specifically abdominal pain and stool frequency in certain patient groups. Clinical improvements are often assessed through symptom severity scores and quality of life evaluations, with several studies indicating notable enhancements compared to placebo. Nonetheless, the impact on gut permeability and microbiome composition varies and might be influenced by the unique microbiota profiles of individual patients (1, 2, 3)
Based o…