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5-HT2B receptor inverse agonists are compounds that bind to the 5-HT2B receptor and reduce its basal activity.
5-HT2B receptor inverse agonists work by binding to the 5-HT2B receptor and stabilizing its inactive conformation. This action leads to a reduction in the receptor's basal activity, which is in contrast to agonists that increase activity and neutral antagonists that simply block the receptor without affecting its basal state.
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