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Binding of bacterial ligands (e.g., postbiotics) induces MYD88 activation and subsequent phosphorylation of IKK complex. NFKB is activated and translocates to the nucleus. Here, NLRC5 (NOD-like receptor family CARD Domain-Containing Protein 5) is induced ; activated NLRC5 shuttles between nucleus and cytosol. The pathway results in a postbiotic-mediated upregulation of [MHC class I / HLA class I human](b…