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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Sialoglycans / Sialylated glycans & Tumor Microenvironment (TME)

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Aberrant Sialoglycans / Sialylated glycans Expression in the Tumor Microenvironment (TME) Can Promote Immunosuppression
van de Wall et al. 2020 Trends in Immunology 41: 274

Mouse B16 melanoma cells with reduced Sialoglycans / Sialylated glycans expression (silenced expression of the sialic acid transporter SLC35A1 / CMP-sialic acid transporter) showed reduced outgrowth compared with control B16 cells
Perdicchio et al. …

Sialoglycans and Siglecs Can Shape the Tumor Immune Microenvironment
van de Wall et al. 2020 Trends in Immunology 41: 274
Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells
Perdicchio et al. 2016 Oncotarget 7: 8771-8782

7/1/2026