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Human GBP1 can directly bind to the lipopolysaccharide (LPS) of Gram-negative bacteria.
Human GBP1 is a 65-kilodalton protein comprising an N-terminal GTPase domain and a C-terminal helical domain (CTHD).
Guanylate-binding protein 1 (GBP-1) is one of the proteins the most highly induced by IFN-gamma…