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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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FOLFIRINOX + PEGPH20 ( PEGylated Recombinant Human Hyaluronidase) - Pancreatic Cancer

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This meta-analysis showed that PEGPH20 did not improve the PFS or OS. Moreover, there was an increased incidence of serious adverse events using PEGPH20 compared to standard therapies.
Solipuram et al. 2021 Current Cancer Therapy Reviews 17(4): 255-260…

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Efficacy and Safety of PEGPH20 in Pancreatic Cancer: Systematic Review and Meta-analysis
Solipuram et al. 2021 Current Cancer Therapy Reviews 17(4): 255-260
Review
Phase IB/II Randomized Study of FOLFIRINOX Plus Pegylated Recombinant Human Hyaluronidase Versus FOLFIRINOX Alone in Patients With Metastatic Pancreatic Adenocarcinoma: SWOG S1313
Ramanathan et al. 2019 JCO 37: 1062–1069

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7/1/2026

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FOLFIRINOX + PEGPH20 ( PEGylated Recombinant Human Hyaluronidase) - Pancreatic Cancer

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