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Despite the well-established role of the gut microbiome in inflammatory bowel disease (IBD), less is known about its longitudinal changes and how these relate to clinical disease activity and fecal calprotectin (f-calprotectin) levels.
The gut microbiome changed significantly during the first year after IBD diagnosis. Alfa diversity increased significantly (P < .001). Significant changes in the relative abundance of bacterial taxa were observed. Changes in alfa div…