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The chimeric CH129 developed to target sialyl-di-Le-a -containing glycoproteins has shown to bind to colorectal, pancreatic, gastric and ovarian tumors (= Antibody-Drug-Conjugates (ADCs))
Conjugation of CH129 to either MMAE or maytansinoid (DM1 and [DM4](brain://99v0evLibUedlXugWgd_LA…