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The role of Transforming growth factor beta (TGF-beta) for T helper 17 cell (Th17) cell differentiation is still controversial. T helper 17 cell (Th17) cells can occur in the absence of Transforming growth factor beta (TGF-beta in the gut mucosa
However, Transforming growth factor beta (TGF-beta) can negatively regulate Th1 and Th2 while promoting T helper 17 cell (Th17) differentiation and therefore favors the contribution of T helper 17 cell (Th17)
Qin et al. 200…