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VSL#3 has been shown to be effective in treating Irritable bowel syndrome (IBS) in both children and adults, according to evidence from randomized trials (2-5).
In a systematic review and meta-analysis, there appeared to be a trend towards improvement in overall response with VSL#3. However, there was no clear evidence of its effectiveness for Irritable Bowel Syndrome (IBS). The trials conducted were limited in number and sample size, and the overall quality of evidence for three out of the five outcomes was considered low. Therefore, larger trials that evaluate validated endpoints in well-defined IBS patients are necessary (6)…